Syntheses of cascade molecules.
نویسندگان
چکیده
منابع مشابه
Syntheses of marine molecules
The enantioselective total syntheses of (-)(E)ybisabolene-8,9-epoxide, (+) (2S,6R)-2-bromo-13-chamigrene, and (+)-chamigrene, important intermediates in the biosynthesis of natural sesquiterpenoids isolated from algae of the genus Laurencia, are described. The compounds are synthesized with regio ñd stereocontrol by using simple forms of bridged intermediates. This represents a general strategy...
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Our group focuses on synthesising biologically active compounds for the various stages of drug development. Several of our projects are devoted to the development of basic synthetic methodology, with a special emphasis on asymmetric synthesis, while others address the synthesis of compounds of known therapeutic interest, in which emphasis is placed on the reliability, efficiency and scalability...
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Reaction of substituted-aniline (8) with ethyl (l-methyl-5-nitroimidazole-2- carbonyl) acetate (9) gave 4-hydroxy-2-(l-methyl-5-nitro-2-imidazolyl)- substituted-quinolines (lo), which were converted to compound 11 with phosphorus oxychloride. Substituted-2-(l-methyl-5-nitro-2-imidazo1yl)-4.- methyl-(or phenyl-) quinolines (14) were prepared through the reaction of 2- acetyl-5-nitro-1-methy...
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ژورنال
عنوان ژورنال: Journal of Synthetic Organic Chemistry, Japan
سال: 1989
ISSN: 0037-9980,1883-6526
DOI: 10.5059/yukigoseikyokaishi.47.62